OligoKS:  The Oligo Kinetics Simulator represents a breakthrough in our understanding of oligonucleotide hybridization kinetics and competing unimolecular folding kinetics.  The OligoKS predicts rate constants for folding and hybridization from the sequence and solution conditions, then it automatically sets up the differential equations and lastly solves the equations for the concentrations of all species as a function of time.   OligoKS has several important applications including fast cycling PCR and microarray probe hybridization.