Over 20 years ago, Dr. John SantaLucia made significant discoveries ​at a prestigious research university ​regarding the behavior of DNA and his seminal published work has now been cited over 5000 times.   He wondered what was possible if he ​incorporated​ the accuracy​ of his predictive models ​into​ software algorithms. Could these algorithms ​​significantly improve, if not replace, traditional trial and error experimentation? He founded DNA Software, Inc. to ​commercialize this research for real market applications.

DNA Software (DNAS) has now ​offered solutions to some of the most difficult problems in ​DNA Diagnostic Design and Analysis, ​first in desktop software and now in cloud based applications as our technology has evolved. These DNAS solutions include primer design multiplexes (500+), detecting DNA copy number from PCR curves, determining complete modified nucleotide predictions and predicting rate kinetics from sequence​ along with a host of solutions currently under development​.  We​ have​ accelerated ​the ​discovery ​timeline ​for our customers from months to minutes and in many cases provided solutions that were otherwise ​im​possible without the expertise of DNAS.