Assay Design and Optimization Training
Ann Arbor, MI – August 20th, 2009 – DNA Software, Inc. just completed a successful, two day training of assay design at its new offices in downtown Ann Arbor, MI.
The first day of training on assay design focused on the science of nucleic acid thermodynamics, basic and advanced function in Visual OMP™, advanced assay design including multiplex PCR and microarrays, as well as high-throughput and scripting applications for DNA Software’s Developer Edition™ products.
The second day of training included an overview of DNA Software’s newly released Modifieds™ module. This new add-on feature for Visual OMP™ allows users to simulate and develop assays that incorporate modified nucleotides. It contains thermodynamic parameters for LNA, PNA, Morpholino, DeoxyU, Inosine, Iso-C, and Iso-G in the context of DNA and RNA. The ThermoBLAST™ module, algorithm, and science were also reviewed during the second day. ThermoBLAST™ represents a much more accurate method than BLAST to check your assay designs against whole genomes to ensure they do not mishybridize to unintended targets. As with previous training classes, part of the class was dedicated to customers’ specific research projects.
Given the success of this class DNA Software is proposing a class in Amsterdam in mid-October and another one in Ann Arbor in later November. If you are interested in joining us for either of these training sessions, please contact:firstname.lastname@example.org or call +1 734 222 9080.
About DNA Software, Inc.
DNA Software, Inc. was founded in 2000 to commercialize the advances in nucleic acid chemistry discovered by world-renowned expert Dr. John SantaLucia, Jr. (the company’s Chief Scientific Officer). DNA Software’s technologies have become the standard of excellence for nucleic acid research and diagnostics development.
DNA Software is a unique software company considering that it conducts original wet lab research. The company’s software programs are the most accurate and comprehensive tools available because their advanced algorithms and models are driven by a large database of thousands of diverse, wet lab-derived, experimental results. DNA Software’s tools correctly design and simulate complicated experiments on the first attempt. Customers can simulate thousands of experiments with the software before running a single experiment in a wet lab. Thus, DNA Software’s technologies save customers significant time, resources, and money that would have been wasted on trial-and-error experimentation.
DNA Software offers contract research, custom software development, commercial web applications, and scientific consulting for nucleic acid research. The company also licenses packaged software tools that help scientists quickly and accurately develop new assays, diagnostics, and therapeutics. OMP™ (Oligonucleotide Modeling Platform™), the core engine that runs all of DNA Software’s tools, models in silico the folding and hybridization of nucleic acids with exceptional accuracy. Visual OMP™ is a platform program for the design, simulation, and analysis of probes/primers, RT-PCR, qPCR, Multiplex PCR, Taqman, Beacons, Scorpions, Microarrays, SNP detection, FRET assays, RNAi, LATE-PCR, plus new formats. OMP Developer EditionTM (OMP DE™) brings customizable, command line, high-throughput computing power to large assay design projects or enterprise applications. ThermoBLAST™ quickly and accurately scans DNA and RNA against genome databases, identifies all off-target hybridizations, and tells you if these mishybridized probes/primers are extensible by polymerase. Modifieds™ allows you to simulate and develop assays that incorporate modified nucleotides (e.g. LNA, PNA, Morpholino, DeoxyU, Inosine, Iso-C, and Iso-G).
The company has recently expanded its original DNA and RNA-based, molecular biology solutions to include modified nucleotides, oligonucleotide kinetics, and structural biology.