DNA team to Present Oligonucleotide Hybridization

Ann Arbor, Mich. – March 8, 2003 — Dr. Svetlana Morosyuk, DNA Sofware director of research, will present DNA Software’s scientific and software advancements like Oligonucleotide Hybridization as they relate to gene quantification at Cambridge Healthtech’s “Profiling PCR and Beyond” in Baltimore, Maryland.

Dr. Morosyuk will present DNA Software’s latest version of in silico environment, Visual OMP™, that is useful for designing gene quantification assays involving PCR, DNA probes, and microarrays. Visual OMP™ uses a comprehensive model of nucleic acid thermodynamics and includes algorithms for calculating the concentration of all species in an assay at any temperature. Visual OMP™ also includes the ability to predict an outcome of a single-target PCR reaction. This useful feature accounts for suboptimal primer binding, target folding, and 3’ extendibility of non-desired structures, which may occur during PCR. It allows users to explore the effects of different ingredient concentrations and annealing temperatures. The software can also be used to design and simulate PCR reactions in the presence of probe(s) and multiple primer pairs.

About DNA Software, Inc.
DNA Software, Inc. combines science and software to enable industrial genomics through advances in technologies based on nucleic acids. The company’s first software platform, OMP™ (Oligonucleotide Modeling Platform™) models in silico the folding and hybridization of single-stranded nucleic acids with great accuracy. The company combines OMP™ with scientific consulting, custom software development, and custom laboratory research to deliver state-of-the-art support for designing and developing of nucleic acid based technologies.