Early identification of pathogens is essential for limiting development of therapy-resistant pathogens and mitigating infectious disease outbreaks. Most bacterial detection schemes use target-specific probes to differentiate pathogen species, creating time and cost inefficiencies in identifying Read more ›
A world class agricultural company compared the capabilities of Assure-CNV to their current workflow. This customer found Assure-CNV increased accuracy with 12 standard deviations versus the 8 provided by their traditional method. Their standard workflow also Read more ›
Most researchers use naïve strategies to design antisense oligonucleotides. However, to maximize assay sensitivity and specificity one must consider probe and target sequence and their respective and combined chemistries. Read more ›
This conversation is consistent with our feedback from customers throughout the years. Building a successful multiplex is hard, expensive and time-consuming. Often times we work with customers after they’ve already tried “going it alone”. We unfortunately Read more ›
InSilixa Inc. and DNA Software Inc. enter into agreement to develop state-of-the-art high-multiplex infectious disease panels for commercialization on InSilixa’s CMOS biochip platform
See press coverage at Genome Web
Infectious disease molecular diagnostic (MDx) assays developed in partnership with inSilixa Read more ›
This question has been a common theme among DNAS customers since our inception 15 years ago. Whether the multiplex is used as a molecular diagnostic or for gene enrichment libraries for NGS,
Not too many people believe this myth, and yet their actions are somewhat irrational as they proceed to immediately use that approach to try to experimentally optimize a multiplex
To minimize mispriming, several PCR texts suggest performing a BLAST search, and such capability is a part of some primer design packages such as
A common artifact in PCR is the amplification of “primer dimers.” The most common conception of the origin of primer dimers is that two primers hybridize at their 3′-ends
PCR