PanelPlex™
Multiplex PCR design software for cancer panels, anti microbial resistance, other and other applications.
Providing completely automated design of multiplex PCR (Polymerase chain reaction) with unprecedented coverage, sensitivity and specificity.
We’ve spent over 20 years thinking about Multiplex PCR so you don’t have to.
PanelPlex™ has been rigorously validated for the detection of numerous viruses, bacteria and human targets.
PanelPlex™ solves these problems by addressing the following:
- PanelPlex™ saves several months (6-9 months on average) of iterative experimental trial-and-error optimization.
- Produces diagnostic quality designs.
- Automated consensus design of multiple variants of DNA or RNA targets.
- PanelPlex™ uses ThermoSleuth™ “playlists” to scan for off-target hybridizations that cause false-positive tests.
- Increase your business by scaling your multiplex PCR assay design process – make more assays, faster time to market, and with higher efficacy.
- Designs around a wide variety of potential artifacts.
Learn more about the four most commonly encountered problems in multiplex panel design.
We think about the design cycle.
Common challenges in multiplex panel design include a lengthy and costly design cycle. This can often be the result of both a knowledge gap within the organization along with freeware and suboptimal design tools. We often see researchers relying on outdated, antiquated tools. If assay design is mission critical to your organization, why would you want to use a suboptimal tool?
“I have been using DNA Software for a long time, at least 8 years. I want to have the best tools available and that is why we use it.”
PanelPlex Packages
Base Package
With a base PanelPlex license, each licensed user (seat) can:
- Access PanelPlex software through a secure WebUI portal.
- Design singleplex PCR primers/probes for dozens or targets at a time (batch mode).
- Include assay background genomes to build designs that avoid unwanted amplifications.
- Add and account for fluorophores/quenchers/tails in assay design oligos.
- Review comprehensive PCR assay design results.
- Execute up to 2 concurrent PCR assay design jobs.
- Execute up to 100 hrs of hosted hybridization analysis with unlimited results storage.
- Share target sequences and analysis results with other users.
Multiplexing Package
- Design Multiplexed PCR assays with minimized cross hybridizations and background sequence interference.
- Add static control assay oligos to new multiplex design jobs.
- Design multiplexed assays from static singleplex predesign oligos (Singleplex-to-multiplex).
Variant Package
- Design variant detection probes optimized to hybridize Small Nucleotide Variations (SNVs) in a target genome.
- Design multiple probes per target.
- Include nucleotide modifications in primer/probe design.
Shared Primers Package
- Design primers that function across multiple targets, and/or in conjunction with alternate primer partners.
Tiling Package
- Design multiplexed primers to generate tiled amplicons across a large target region.ross multiple targets, and/or in conjunction with alternate primer partners.
How Can We Help?
The easiest way to move past your PCR challenges is for our team to hear first hand what you’re looking to accomplish and demonstrate how our platform and team can help you on your journey. We want to see you move as fast as possible with your breakthrough research. Time is money. Let us help you get past this roadblock.